1,1-DIANISYL-2,2,2-TRICHLOROETHYL ETHERS - A NEW PROTECTION FOR THE HYDROXYL GROUP

beta-Haloalkyl protecting groups are well established. However, there was a lack of an appropriate protection, especially for carboxyl and v icinal hydroxyl groups. This problem was now solved by design of the 1 ,1-dianisyl-2,2,2-trichloroethyl group (DATE). The alkylation of model alcohols with the DATE moiety is described. The resulting beta-haloal kyl ethers proved to be remarkable stable against acids and bases. Deb locking of the model alcohols is achieved in high yields.