EFFECT OF METHACHOLINE ON MUCOCILIARY TRANSPORT IN BOVINE TRACHEA IN-VITRO

Authors
MARS MH HENRICKS PAJ HAJER R BREUKINK HJ
Citation
Mh. Mars et al., EFFECT OF METHACHOLINE ON MUCOCILIARY TRANSPORT IN BOVINE TRACHEA IN-VITRO, American journal of veterinary research, 56(4), 1995, pp. 486-488
Citations number
33
Categorie Soggetti
Veterinary Sciences
Journal title
American journal of veterinary research → ACNP
ISSN journal
00029645
Volume
56
Issue
4
Year of publication
1995
Pages
486 - 488
Database
ISI
SICI code
0002-9645(1995)56:4<486:EOMOMT>2.0.ZU;2-G
Abstract
A method is described to evaluate pharmacologic influence on bovine tr acheal mucus transport in vitro. in this model, cholinergic agonist me thacholine stimulated transport velocity. Methacholine at concentratio n of 10(-6)M increased velocity by 13.6%, whereas 10(-5)M increased ve locity by 26%. Stimulation was inhibited by atropine.