A child of 10 years 5 months presenting with chronic renal failure had
bilateral cystic kidneys. Biopsy of a right lower-pole solid mass rev
ealed nephroblastoma. At bilateral nephrectomy, both kidneys were both
replaced by variable-sized cysts with a unifocal nephroblastoma on th
e right. Renal failure with nephroblastoma is uncommon and is usually
either a manifestation of the Drash syndrome or a complication of chem
otherapy. The need to assess both kidneys in a child with any other re
nal abnormality in addition to a renal mass should always be considere
d.