THE STUDY OF THE MECHANISM OF PERMETRIN A CTION ON HOUSE-DUST MITES

The mechanism of permetrin action on two home dust mite species: Derma tophagoides farinae and D. pteronyssinus. Both species turned out to b e resistant to permetrin under different conditions of toxicity evalua tion. A factor of cuticle permeability was investigated. The impact of monoxygenases and esterases in the permetrin detoxication mechanism w as shown. The spectra of esterase complexes of enzymes was examined by means of electrophoresis in PAAG; in addition, the zones of esterase activity were identified with the help of two substrates: 2-NA and ATI . The qualitative differences of the esterase complexes of enzymes of both species were found.