CRYSTAL-STRUCTURES OF A D-RESIDUE CONTAINING TETRAPEPTIDES .1. TERT-BOC-D-VALYL-ALANYL-LEUCYL-ALANYL METHOXIDE, BUTANOL SOLVATE

Authors
BOBDE V DURANI S PATTABHI V SADASIVAN C
Citation
V. Bobde et al., CRYSTAL-STRUCTURES OF A D-RESIDUE CONTAINING TETRAPEPTIDES .1. TERT-BOC-D-VALYL-ALANYL-LEUCYL-ALANYL METHOXIDE, BUTANOL SOLVATE, International journal of peptide & protein research, 45(4), 1995, pp. 332-336
Citations number
12
Categorie Soggetti
Biology
Journal title
International journal of peptide & protein research → ACNP
ISSN journal
03678377
Volume
45
Issue
4
Year of publication
1995
Pages
332 - 336
Database
ISI
SICI code
0367-8377(1995)45:4<332:COADCT>2.0.ZU;2-P
Abstract
The crystal structure of a heterochiral peptide, viz. Boc-D-Val-Ala-Le u-Ala-OMe, with a D-residue in the beginning of the sequence has been determined (a = 9.464(5), b = 35.615(5), c = 9.703(2) Angstrom, space group P2(1)2(1)2, Z = 4, R = 0.09). The peptide is in the extended bet a-conformation and the packing is stabilised by four N-H...O hydrogen bonds in an antiparallel beta-sheet arrangement. The solvent molecule is disordered and does not have any specific interactions with the pep tide. (C) Munksgaard 1995.