USNIC ACID AND DIFFRACTAIC ACID AS ANALGESIC AND ANTIPYRETIC COMPONENTS OF USNEA-DIFFRACTA

Authors
OKUYAMA E UMEYAMA K YAMAZAKI M KINOSHITA Y YAMAMOTO Y
Citation
E. Okuyama et al., USNIC ACID AND DIFFRACTAIC ACID AS ANALGESIC AND ANTIPYRETIC COMPONENTS OF USNEA-DIFFRACTA, Planta medica, 61(2), 1995, pp. 113-115
Citations number
6
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
61
Issue
2
Year of publication
1995
Pages
113 - 115
Database
ISI
SICI code
0032-0943(1995)61:2<113:UAADAA>2.0.ZU;2-P
Abstract
Diffractaic acid and usnic acid were identified as the analgesic and a ntipyretic components of a lichen, Usnea diffracta. Both compounds sho wed an analgesic effect by the acetic acid-induced writhing and tail-p ressure methods in mice. Regarding the effect on normal body temperatu re and LPS-induced hyperthermia in mice, diffractaic acid showed a sig nificant effect only on the former and usnic acid only on the latter.