DIRECT ENANTIOMERIC SEPARATION OF FLAVANONES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY USING VARIOUS CHIRAL STATIONARY PHASES

Authors
FICARRA P FICARRA R BERTUCCI C TOMMASINI S CALABRO ML COSTANTINO D CARULLI M
Citation
P. Ficarra et al., DIRECT ENANTIOMERIC SEPARATION OF FLAVANONES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY USING VARIOUS CHIRAL STATIONARY PHASES, Planta medica, 61(2), 1995, pp. 171-176
Citations number
22
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
61
Issue
2
Year of publication
1995
Pages
171 - 176
Database
ISI
SICI code
0032-0943(1995)61:2<171:DESOFB>2.0.ZU;2-T
Abstract
The performance of four chiral liquid chromatographic columns (Chiralc el(R) OA, OJ, OC, OD) was studied with respect to the enantioseparatio n of flavanones and some derivatives. The effect of mobile phase compo sition on the retention time and stereoselectivity was studied. A good enantioseparation (a up to 1.45) was achieved for most of the racemat es. Further, the elution order of the enantiomers from the chiral stat ionary phases has been determined by using a circular dichroism based detection system.