EFFECT OF COMPRESSION STOCKINGS ON THE SKIN MICROCIRCULATION IN CHRONIC VENOUS INSUFFICIENCY

Objective: To use a single fibre laser Doppler fluxmeter to assess the microcirculatory effects of compression stockings. Design: Controlled study comprising patient and control groups. Setting: Department of S urgery, University College London Medical School, London, UK. Patients and participants: Ten patients with lipodermatosclerosis caused by ch ronic venous insufficiency and 10 control subjects. Interventions: Mea surements were made from the liposclerotic skin of patients and 8 cm a bove the medial malleolus in controls. Laser Doppler flux (LDF), blood cell velocity (BCV) and concentration of moving blood cells (CMBC) we re recorded with the subject lying supine. A class II graduated compre ssion stocking was applied to the leg and laser Doppler recordings wer e repeated. The protocol was repeated with the subject sitting. Main o utcome measures: The effects of a compression stocking on LDF, BCV and CMBC in the horizontal and sitting positions were measured. Results: In patients in the supine position, the compression stocking resulted in a 28% median increase in LDF (p = 0.03), with a corresponding 29% m edian increase in BCV. There was no significant change in CMBC. In the sitting position, the compression stocking caused a 105% median incre ase in LDF (p<0.01) due to a corresponding 89% median increase in BCV (p = 0.01); there was only 25% median increase in CMBC. The effects of compression in controls were similar to those in patients. Conclusion : Compression stockings may be effective in the treatment of chronic v enous insufficiency by increasing the microcirculatory flow velocity.