5-AMINO-3H-1,2,4-DITHIAZOLE-3-THIONE AS A SYNTHON - NEW SYNTHESIS OF 2-THIOUREIDOBENZHETEROAZOLES

New and efficient one pot syntheses of 2-thioureidobenzimidazole (V), 2-thioureidobenzoxazole (VI), and 2-thioureidobenzothiazole (VII) have been developed. The target compounds were obtained in good yields by condensing the title synthon commonly known as isoperthiocyanic acid ( I) with 1,2-diaminobenzene (II), 2-aminophenol (III), and 2-aminothiop henol (IV), respectively, in various organic solvent and in the solid state.