J. Fareed et al., MOLECULAR MARKERS OF HEMOSTATIC ACTIVATION - IMPLICATIONS IN THE DIAGNOSIS OF THROMBOSIS, VASCULAR, AND CARDIOVASCULAR DISORDERS, Clinics in laboratory medicine, 15(1), 1995, pp. 39-61
Until recently, the diagnosis of thromboembolic disorders remained dif
ficult to establish before the occurrence of a pathologic event. Clear
ly, thrombosis is the result of a progressive alteration of the blood
and vasculature. Various molecular markers of hemostatic alteration ar
e found in increased or decreased amounts predisposing to thrombosis o
r in increased circulating amounts during the activation process.