ANEMIA AND PLASMODIUM-FALCIPARUM INFECTIONS AMONG YOUNG-CHILDREN IN AN HOLOENDEMIC AREA, BAGAMOYO, TANZANIA

Although the aetiology of anaemia in tropical areas is multifactorial, Plasmodium falciparum malaria is commonly associated with anaemia in children living in holoendemic malaria areas. Such an association was examined in a population based study of 338 children 6 to 40 months of age living in the Bagamoyo area of Tanzania. Stepwise regression anal ysis showed that fever and parasitaemia were effective in predicting a naemia and that the anaemic condition was age dependent. The majority of the children were iron deficient, followed by normochromic macrocyt ic anaemias. There was strong evidence in this age group that the anae mia was associated with malaria and not geohelminth infection. The imp ortance of malaria and anaemia as a cause of childhood morbidity in Af rica is discussed. This condition has taken on new significance with t he realization that blood transfusions commonly used to treat severe a naemia are a major vehicle for Human Immunodeficiency Virus (HIV) tran smission.