D. Schwender et al., MIDLATENCY AUDITORY-EVOKED POTENTIALS AND WAKEFULNESS DURING CESAREAN-SECTION, European journal of anaesthesiology, 12(2), 1995, pp. 171-179
We investigated intra-operative wakefulness and mid-latency auditory e
voked potentials (MLAEP) in 20 patients undergoing elective Caesarean
section under general anaesthesia. Anaesthesia was induced with thiope
ntone 5 mg kg(-1) i.v. and succinylcholine 1-1.5 mg kg(-1) i.v. After
delivery, a balanced anaesthetic technique was maintained using fentan
yl 0.2-0.3 mg i.v., enflurane 0.4-1.0 vol% end-expired concentration a
nd 50% N2O in oxygen. Purposeful movements were interpreted as signs o
f inadequate anaesthesia and intra-operative wakefulness. They were re
corded as either spontaneous movements or in response to one of two au
dio tapes (tape A: sound of a crying baby; tape B: classical music). P
ost-operatively, intra-operative dreams, hallucinations and detailed r
eports about intra-operative events were evaluated. Auditory evoked po
tentials were recorded online before and during general anaesthesia. T
wenty spontaneous purposeful movements were observed in 12 patients, s
even before or during delivery and 13 after delivery. Four purposeful
movements were observed after presentation of the sound of a crying ba
by but only one after classical music. Dreams and hallucinations were
reported by nine patients. Two patients reported experiencing surgical
manipulations. In the awake state MLAEPs had great peak-to-peak ampli
tudes and a periodic waveform. Under adequate levels of general anaest
hesia MLAEPs showed a marked increase in latency and decrease in ampli
tude or were even suppressed completely. This increase in latencies an
d decrease in amplitude of MLAEP was absent in patients who reported i
ntraoperative events and during spontaneous or provoked motor reaction
s.