CLONING AND SEQUENCE-ANALYSIS OF HUMAN THYROID TRANSCRIPTION FACTOR-1

Authors
SAIARDI A TASSI V DEFILIPPIS V CIVITAREALE D
Citation
A. Saiardi et al., CLONING AND SEQUENCE-ANALYSIS OF HUMAN THYROID TRANSCRIPTION FACTOR-1, Biochimica et biophysica acta, N. Gene structure and expression, 1261(2), 1995, pp. 307-310
Citations number
8
Categorie Soggetti
Biology,Biophysics,"Biothechnology & Applied Migrobiology
Journal title
Biochimica et biophysica acta, N. Gene structure and expression → ACNP
ISSN journal
01674781
Volume
1261
Issue
2
Year of publication
1995
Pages
307 - 310
Database
ISI
SICI code
0167-4781(1995)1261:2<307:CASOHT>2.0.ZU;2-R
Abstract
The thyroid transcription factor 1 (TTF-1) is a homeodomain-containing transcription factor that activates the transcriptional activity of t hyroid-specific gene promoters by binding to them. Hence, TTF-1 is cru cial in the maintenance of the thyroid differentiation phenotype. The authors isolated and analysed the human TTF-1 gene, which shows a stri king homology with the rat TTF-I gene.