PREOPERATIVE AUTOLOGOUS BLOOD DONATION AN D ITS SIGNIFICANCE FOR PULMONAL LOBECTOMIES

Citation
K. Hallfeldt et al., PREOPERATIVE AUTOLOGOUS BLOOD DONATION AN D ITS SIGNIFICANCE FOR PULMONAL LOBECTOMIES, Zentralblatt fur Chirurgie, 120(3), 1995, pp. 228-233
Citations number
NO
Categorie Soggetti
Surgery
Journal title
ISSN journal
0044409X
Volume
120
Issue
3
Year of publication
1995
Pages
228 - 233
Database
ISI
SICI code
0044-409X(1995)120:3<228:PABDAD>2.0.ZU;2-B
Abstract
It was the aim of the underlying study to determine the value of preop erative autologous blood donation and its importance with regard to pu lmonal lobectomies. Over the course of three years and a total number of 220 operations, autologous blood was preoperatively deposited in 74 cases. 21 patients did not meet the criteria for autologous blood don ation and hence, were omitted from the study. It was found that only 5 .4% of the patients who had donated autologous blood required a homolo gous blood transfusion versus 27.2% in the non-donor group. This would imply, that the necessity for homologous blood transfusion is reduced by approximately 80% in patients depositing autologous blood prior to surgery. Observing a similar haemoglobin in both groups at admission, it was found that autologous blood donors went into surgery with an h b 1.5 g/dl lower than non donors; the levels however adjusting themsel ves immediately postoperatively. No increased complication rate was fo und as a result of preoperative autologous blood donation. The data in dicate that only 30% of patients undergoing pulmonal lobectomy require homologous blood tranfusions. 80% of these patients could profit from preoperative autologous blood donation. For 70% of all patients the p rocedure would be of no benefit. Bearing in mind the immunosuppressive effect of homologous blood transfusions, which may result in a higher rate of tumor recurrence, we find preoperative autologous blood donat ion a justifiable procedure even under these circumstances. It would h owever he beneficial if studies were conducted hereby investigating to what extent similar results could be achieved by preoperative acute i sovolemic hemodilution.