ACCUMULATION OF ADE(-CEREVISIAE ALLELIC IN RAD6 DURING ADENINE STARVATION() REVERSIONS IN ISOAUXOTROPHIC STRAINS OF SACCHAROMYCES)

Authors
STORCHOVA Z GIL APR JANDEROVA B VLASAK J VONDREJS V
Citation
Z. Storchova et al., ACCUMULATION OF ADE(-CEREVISIAE ALLELIC IN RAD6 DURING ADENINE STARVATION() REVERSIONS IN ISOAUXOTROPHIC STRAINS OF SACCHAROMYCES), Folia microbiologica, 42(1), 1997, pp. 47-51
Citations number
9
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology
Journal title
Folia microbiologica → ACNP
ISSN journal
00155632
Volume
42
Issue
1
Year of publication
1997
Pages
47 - 51
Database
ISI
SICI code
0015-5632(1997)42:1<47:AOAAIR>2.0.ZU;2-K
Abstract
A comparative method based on an analysis of accumulation of starvatio n-induced Ade(+) reversions and cell death during adenine starvation w as developed and exploited for estimating the role of RAD6 in the star vation-induced reversions. It was shown that inactivation of RAD6 func tion in Saccharomyces cerevisiae markedly enhances the accumulation of Ade(+) reversions, and therefore it is likely that this gene is takin g part in maintaining the low level of starvation-induced mutations in yeast cells.