SYNTHESIS OF 6-ETHYLOCTADECANOIC AND 9-ETHYLOCTADECANOIC ACIDS

Authors
DRAGAS D TANOJO H BRUSSEE J JUNGINGER HE BODDE HE
Citation
D. Dragas et al., SYNTHESIS OF 6-ETHYLOCTADECANOIC AND 9-ETHYLOCTADECANOIC ACIDS, Archiv der pharmazie, 329(10), 1996, pp. 465-467
Citations number
14
Categorie Soggetti
Chemistry,"Pharmacology & Pharmacy
Journal title
Archiv der pharmazie → ACNP
ISSN journal
03656233
Volume
329
Issue
10
Year of publication
1996
Pages
465 - 467
Database
ISI
SICI code
0365-6233(1996)329:10<465:SO6A9A>2.0.ZU;2-#
Abstract
Specific branched fatty acids are of great interest in the search of a new type of drug penetration enhancers across human skin for transder mal drug delivery and in gaining an understanding of structure-activit y relationships with skin lipids. A convenient synthesis thesis has th erefore been developed especially for ethyloctade-canoic acids. The su ccessful syntheses of 6- and 9-ethyloctadecanoic acids are reported he re.