DEVELOPMENT OF SPOROGONIC CYCLE OF PLASMODIUM-VIVAX IN EXPERIMENTALLYINFECTED ANOPHELES-ALBIMANUS MOSQUITOS

The sporogonic cycle of Plasmodium vivax was established and maintaine d under laboratory conditions in two different strains of Anopheles al bimanus mosquitoes using as a parasite source blood from human patient s or from Aotus monkeys infected with the VCC-2 P.vivax colombian isol ate. Both the Tecojate strain isolate from Guatemala and the Cartagena strain from the colombian Pacific coast were susceptible to infection s with P.vivax. A higher percentage of Cartagena mosquitoes was infect ed per trial, however the Tecojate strain developed higher sporozoite loads. Intravenous inoculation of Aotus monkeys with sporozoites obtai ned from both anopheline strains resulted in successful blood infectio ns. Animals infected with sporozoites from the Tecojate strain present ed a patent period of 21-32 days whereas parasitemia appeared between days 19-53 in monkeys infected with sporozites from Cartagena strain.