We report here a 14-year-old girl with diffuse partial woolly hair. Th
e patient presented mild hair loss associated with the presence of fin
e, short and kinky hairs closely interspersed with the normal hair thr
oughout the scalp. The pathology of the scalp revealed the presence of
intermediate-sized hair follicles regularly intermingled with normal
follicles in each follicular unit. The possibility that diffuse partia
l woolly hair may result from a progressive miniaturization of the hai
r follicles may explain the presence of evident hair thinning in sever
al adult patients affected by this rare abnormality.