This study assessed the postoperative microvascular hemodynamics in en
d-to-side arterial anastomoses of varied angles in order to determine
whether the angle of the anastomosis affects arterial flow, Thirty mal
e rats were divided into three groups of ten. Carotid to carotid end-t
o-side anastomoses were performed with anastomotic angles of 45, 90, a
nd 135 degrees. Postoperative flow was assessed using high frequency p
ulsed Doppler ultrasound (HFPDU) at 30 and 120 min postoperatively, Me
asurements at 30 min demonstrated significant differences in flow, wit
h the 45 degrees grafted vessels utilizing 56.5% of total carotid flow
, and the 90 degrees and 135 degrees anastomoses appropriating 46.5% a
nd 43.2% of flow, respectively (comparing 45 degrees to both 90 degree
s, P < 0.05, and 135 degrees, P < 0.002). The change from baseline in
45 degrees and 90 degrees groups dissipated over a 2 hr postoperative
period, but flow in the grafted vessels in the 135 degrees group conti
nued well below 50% at 39.9% (comparing to both 45 degrees and 90 degr
ees, P < 0.001), thereby displaying a significant difference in the po
stoperative arterial flow of varied angled microanastomoses. (C) 1995
Wiley-Liss, Inc.