IMMUNOPATHOLOGICAL FINDINGS IN POSTERIOR SCLERITIS

Posterior scleritis can present with a variety of symptoms, and its cl inical diagnosis is therefore difficult. Little is known about the pat hogenesis and the cellular effector mechanisms. This case report prese nts the immunopathological findings of posterior scleritis in the enuc leated eye of a 28-year-old female with no known underlying disease. T he cells infiltrating the scleral fibers consisted predominantly of T cells. Many of them were CD4 cells. Clusters of T and B cells were fou nd in perivascular areas. No signs of primary vasculitis were seen. Th e cellular infiltrate in posterior scleritis shows features compatible with a T-cell-mediated (autoimmune) disorder.