M. Lanier et R. Pastor, RING-OPENING OF BETA-F-ALKYL ALPHA,BETA-EPOXYESTERS WITH NABH4 IN ALCOHOLIC MEDIA, Tetrahedron letters, 36(14), 1995, pp. 2491-2492
We report the preparation of 3-F-alkyl 2-alkoxy propan-1,3-diols (2 =
Et, 3 = Oc). They are obtained from 3-F-alkyl 2,3-epoxypropanoates 1 i
n a one-pot regioselective oxiranic ring alcoholysis and ester reducti
on by NaBH4 in alcoholic media (EtOH, OcOH).