OUTCOME OF PARTIAL SPLENECTOMY FOR TYPE-I GAUCHER DISEASE

Partial splenectomy was introduced to achieve the benefits of splenect omy and to avoid the risk of overwhelming infection in patients with s ymptomatic Gaucher disease. We observed regrowth of the splenic remnan t, reemergence of preoperative symptoms, and new bone involvement amon g most of our patients who had undergone partial splenectomy. Enzyme r eplacement therapy has markedly limited indications for splenectomy, p artial or total, for Gaucher disease.