Ar. Dennis et al., ANALGESIA AFTER CESAREAN-SECTION - THE USE OF RECTAL DICLOFENAC AS ANADJUNCT TO SPINAL MORPHINE, Anaesthesia, 50(4), 1995, pp. 297-299
A double-blind placebo-controlled study was performed to assess the an
algesic effect of rectal sodium diclofenac 100 mg after Caesarean sect
ion using subarachnoid hyperbaric bupivacaine 0.5% and morphine 0.2 mg
. During the 48 h follow-up period both placebo and diclofenac groups
had comparable analgesia as measured by visual analogue scores (VAS) a
t rest and on movement. However, diclofenac prolonged the mean time to
first analgesia by more than 5 h from 13 h 45 min in the placebo grou
p to 18 h 58 min (p < 0.03). The incidence of side effects (nausea, vo
miting, itching, excessive lochia loss and the need for additional ana
lgesia) were comparable in each group.