Thyroid gland dysfunction is a relatively common clinical problem in e
lderly people and is associated with significant morbidity if left unt
reated. The clinical features of thyroid disease may be subtle, easily
overlooked or misdiagnosed. Therefore, a high index of suspicion is n
ecessary. If potentially serious sequelae are to be avoided, the selec
tion and interpretation of thyroid function tests must be appropriate.
It is particularly important to consider both the effect of concurren
t illness and the effect of certain drugs on thyroid function tests. W
ith recent methodological advances, thyroid function tests are now mor
e reliable, though in certain situations they still need to be interpr
eted with caution. Once the diagnosis is established, the management o
f both hypothyroidism and hyperthyroidism is relatively simple and eff
ective, though there are special considerations relating to elderly pa
tients.