The biosynthesis of the antibiotic metabolities oosponol and oospoglyc
ol by the fungus Gloeophyllum abietinum has been analysed using C-13-l
abelled acetate, malonate, serine and formate as precursors and C-13 N
MR as the analytical method. The polyketide pathway could be confirmed
. One carbon of the isocoumarin ring originates from serine. Copyright
(C) 1996 Elsevier Science