N. Lippens et al., MULTIPLE CARCINOMAS OF THE SKIN AND CHRON IC LYMPHATIC-LEUKEMIA, Annales de dermatologie et de venereologie, 122(1-2), 1995, pp. 23-25
Introduction. Skin cancer occurs more readily in more aggressive forme
s in immunodepressed subjects. We report the case of a patient with ch
ronic lymphoid leukaemia and multiple skin carcinomas complicated with
carcinomatous lymphagitis. Case report. A 63 year-old man with chroni
c lymphoid leukaemia, stage A in the Binet classification, had multipl
e epidermoid carcinomas on the trunk and face. The skin tumours were c
omplicated with cervical lymph mode metastases, then a prethoracic car
cinomatous lymphangitis with a rapidly fatal clinical course. Discussi
on. Chronic lymphoid leukaemia and lymphomas are associated with a hig
h incidence of skin carcinoma. The immuno-depression inherent in the h
aematologic disease would appear to favor aggressive skin cancers. Our
case was particularly severe since the carcinomatous lymphangitis was
rapidly fatal.