Hypersensitivity reactions to carboplatin are rare but potentially lif
e-threatening complications. A patient with an anaphylactic reaction t
o carboplatin is presented. This patient had received multiple courses
of platinum-based chemotherapy including cisplatin and carboplatin. C
lose patient monitoring during chemotherapy is essential and skin test
ing to identify the etiologic agent is indicated when hypersensitivity
reactions occur in the setting of combination chemotherapy. (C) 1995
Academic Press, Inc.