Until recently, the Listeria genus was thought to be uniformly suscept
ible to antibiotics. Since the first detection in 1988 of a multiply r
esistant strain of L. monocytogenes, other cases of antibiotic resista
nce were described in Listeria spp. Presence of antibiotic resistant s
trains in this bacterial genus should be monitored and genetic support
and epidemiology of resistance should be studied in order to limit th
eir dissemination and adjust antibiotherapy.