Psoriatic arthritis is an inflammatory arthritis with diverse clinical
manifestations, Certain subsets of patients tend to run a more severe
course of erosive disease. A few points are noteworthy: When a diagno
sis of psoriatic arthritis is being considered, ask if there is any fa
mily history of psoriasis and search for skin lesions in all parts of
the body, including the scalp, ears, and genital and anal areas. Rule
out septic arthritis even in a patient with an established diagnosis o
f psoriatic arthritis, especially if the presentation is monarticular,
In cases of fulminant disease, consider checking for HIV infection. P
harmacologic therapy and physical rehabilitation are used in psoriatic
arthritis, Mild cases can be controlled with use of nonsteroidal anti
-inflammatory drugs; in more severe cases, treatment with immunosuppre
ssive or disease-modifying agents is needed.