PARTIAL NEPHRECTOMY IN WELL-RESPONDING STAGE-I WILMS-TUMORS - REPORT OF 3 CASES

We report on 3 of 21 stage I Wilms' tumor patients with tumor volumes of 190, 890, and 1300 mL, respectively, who responded dramatically to preoperative chemotherapy according to the Austrian/Hungarian Wilms' T umor Study 89 by tumor volume reductions to 20%, 23%, and 13%, respect ively. Radical resection of the tumors with renal preservation was ach ieved in all patients. Postoperative studies did not show any function al deficit in the preserved kidney. The patients have been in complete remission for 26, 33, and 60 months, respectively. Our Preliminary re sults indicate that tumor resection should be feasible in patients wit h good responding stage I Wilms' tumors.