This study investigated unawareness of memory loss in 48 severe closed
-head injury patients. Awareness was measured as the correlation of pa
tients' memory test scores with their self-ratings on the Everyday Mem
ory Questionnaire (EMQ). Patients who endorsed atypical memory failure
s on the EMQ were classified as invalid responders. Invalid responders
had poorer memory test performances and a higher rate of focal left h
emispheric lesions, but did not report greater emotional symptoms. Cor
relations between memory test scores and memory self-ratings were weak
er among invalid responders or those classified as depressed, and stro
nger among valid responders, especially those classified as non-depres
sed. The results indicate that the validity of memory self-reports is
influenced by both neurogenic and psychogenic factors, and suggest tha
t invalid responding is an important problem with self-reports by brai
n-injured patients.