The Multiple Air-lift Loop reactor (MAL) is a new type of bioreactor,
in which a series of airlifts with internal loops is incorporated into
one vessel. As such, the MAL is an approximation of an aerated plug-f
low fermenter. Gas/liquid oxygen transfer was studied as a function of
the gas flow rate in a MAL. The second MAL-compartment in the series
was investigated in particular, and a Rectangular Air-lift Loop reacto
r (RAL) was used as a reference. Both a dynamic and a steady-state met
hod were used for the determination of the overall volumetric oxygen-t
ransfer coefficient. Both methods gave the same results. The oxygen tr
ansfer coefficient in the second MAL-compartment was low compared to t
hat of conventional internal-loop reactors. Wall effects probably caus
ed bubble coalescence and a reduction in the oxygen transfer. For the
RAL it was found that oxygen transfer was comparable to that in a bubb
le column.