F. Guilloteau et L. Miginiac, A CONVENIENT REGIOSPECIFIC SYNTHESIS OF ISOTHIAZOL-4-YL DERIVATIVES, Synthetic communications, 25(9), 1995, pp. 1383-1389
Synthesis of derivatives resulting from the formation of a carbon-carb
on bond in 4-position of the isothiazole is easily obtained by using t
he 4-magnesioisothiazole prepared via metal halogen exchange.