FUNGICIDAL, BACTERICIDAL AND ANTIFERTILITY ACTIVITIES OF DIORGANOSILICON(IV) COMPLEXES DERIVED FROM BENZOTHIAZOLINES

Synthetic, structural and biological aspects of trigonal-bipyramidal, Me(2)Si(N-S)Cl and octahedral, Me(2)Si(N-S), types of diorganosilicon( IV) complexes of heterocyclic benzothiazolines (N-SH) are described. T he complexes were characterized by elemental analysis, molecular weigh t determination, conductance measurements and electronic, infrared, H- 1 and C-13 NMR spectroscopic studies. Some ligands and their correspon ding dimethylsilicon(IV) complexes have been tested for their effects on several pathogenic fungi and bacteria and found to be quite active in this respect. Antifertility activity in male mice of some represent ative ligands and their silicon complexes was also evaluated and discu ssed.