Objective: To assess the efficacy acid safety of the removal of pancre
atic duct stones by a combined modality approach in patients with panc
reatic ductal lithiasis and recurrent abdominal pain. Design: Retrospe
ctive review with a mean follow-up of 19 months (range, 1 to 56 months
). Setting: A tertiary care, private community hospital with a univers
ity affiliation. Patients: The records of patients who presented to th
e hospital or who were referred with recurrent abdominal pain and who
were demonstrated to have pancreatic ductal lithiasis between 1989 and
1994 were reviewed. Patients were assessed by their clinical response
to pancreatic duct stone extraction by a variety of therapeutic inter
ventions. Results: Fifteen patients were included in the study. One pa
tient was excluded from analysis because of a concurrent choledochocel
e. Two patients required operative decompression and stone extraction
for endoscopically inaccessible stones. Six patients were treated with
endoscopic management alone, and six were treated with a combination
of extracorporeal shock wave lithotripsy and endoscopic stone retrieva
l. Twelve patients had complete clearance of the pancreatic duct. One
patient had a stone that was not removed, but adequate pancreatic duct
al decompression was achieved. The remaining patient had incomplete cl
earance of pancreatic stone fragments following extracorporeal shock w
ave lithotripsy but had adequate ductal drainage. No patient has requi
red further therapy or hospitalization for abdominal pain. No complica
tions occurred as a result of any intervention in this study. Conclusi
ons: A multidisciplinary combined modality approach is a safe and effe
ctive method for extracting pancreatic duct stones in symptomatic pati
ents. Stone extraction and reestablishment of adequate ductal drainage
appear to relieve symptoms in some patients.