Pn. Matthews et al., INVOLVEMENT OF THE INFERIOR VENA-CAVA BY RENAL TUMOR - SURGICAL EXCISION USING HYPOTHERMIC CIRCULATORY ARREST, British Journal of Urology, 75(4), 1995, pp. 441-444
Objective To evaluate the immediate and long-term results of a radical
surgical technique in the treatment of renal tumours with extensive i
nvolvement of the inferior vena cava (IVC). Patients and methods Seven
patients with extensive involvement of renal tumours into the IVC wer
e operated upon using a cardiopulmonary by-pass, hypothermia and cardi
ac arrest to facilitate surgery. Wide exposure of the IVC in a bloodle
ss field permitted complete removal of all visible tumour in each case
. Histological sections confirmed renal cell cancer in six patients an
d Wilms tumour in a 15-year-old girl. Results All patients recovered w
ell from their surgery with no major complications and spent one or tw
o days in the Intensive Treatment Unit and an average of 13 days in ho
spital after the operation. Of the seven patients, four are alive and
well with no obvious disease after an average follow-up time of 30 mon
ths (range 8-54). The other three patients have died from disseminated
renal cancer. Conclusion This procedure provides good local control o
f the tumour and offers the only hope of cure in patients with this di
sease. In collaboration with the surgical cardiac team it can be safel
y carried out with acceptable morbidity and mortality.