The UKCCCR Register of U.K. Cancer Trials comprises an on-line databas
e of all randomized trials of cancer therapy, whether phase III or ran
domized phase II trials. Both current or open trials, and closed or co
mpleted trials, are included. Abstracts of any publications associated
with the trials are also included. The UKCCCR Register is the initial
component of a larger European register of trials. This article descr
ibes the structure and content of the database, the PC program for dat
a entry, and the Unix-based browsing software for interactive access o
ver networks. Problems of ensuring complete and comprehensive registra
tion of trials, and sources of information, are also reviewed.