HIGH-FLOW PRIAPISM ASSOCIATED WITH SICKLE-CELL DISEASE

Priapism associated with sickle cell disease is classically described as a low flow state. We report 2 cases of high flow priapism associate d with sickle cell disease. High flow priapism has previously been rep orted almost exclusively in patients with traumatic rupture of the cav ernous artery. Neither of our patients had historical or radiographic findings consistent with injury to the penile vasculature. One patient was treated unsuccessfully with intracorporeal injection of methylene blue and 1 underwent successfully bilateral pudendal artery embolizat ion. The pathophysiological mechanism(s) responsible for the productio n of high flow priapism in patients with sickle cell disease is not kn own.