Verruciform xanthoma is a rare benign lesion. The majority of the case
s occur on the oral mucosa. However, other sites, particularly the ano
genital region, may be involved. We report the eleventh case in the li
terature of verruciform xanthoma of the penis. Genital verruciform xan
thoma is significant because it can simulate verrucous carcinoma or in
vasive squamous cell carcinoma. Proper diagnosis by clinical recogniti
on, adequate but limited biopsy and histopathological examination will
avoid unnecessarily aggressive surgical procedures. The pertinent cli
nical and histological features of our case are described and the lite
rature on penile verruciform xanthoma is reviewed.