STUDIES OF THE INDUCIBILITY OF P450-1A IN PERCH FROM THE PCB-CONTAMINATED LAKE-JARNSJON IN SWEDEN

Authors
FORLIN L CELANDER M
Citation
L. Forlin et M. Celander, STUDIES OF THE INDUCIBILITY OF P450-1A IN PERCH FROM THE PCB-CONTAMINATED LAKE-JARNSJON IN SWEDEN, Marine environmental research, 39(1-4), 1995, pp. 85-88
Citations number
11
Categorie Soggetti
Marine & Freshwater Biology","Environmental Sciences",Toxicology
Journal title
Marine environmental research → ACNP
ISSN journal
01411136
Volume
39
Issue
1-4
Year of publication
1995
Pages
85 - 88
Database
ISI
SICI code
0141-1136(1995)39:1-4<85:SOTIOP>2.0.ZU;2-W
Abstract
Comparatively low levels of hepatic EROD activities were observed in f eral perch caught in Lake Jarnsjon, heavily contaminated with polychlo rinated biphenyls (PCBs) when compared to reference sites. On the othe r hand rainbow trout, caged in Lake Jarnsjon, exhibited elevated EROD activities, P450 1A1 protein and CYP1A1 mRNA levels. The feral perch f rom the PCB area were non-responsive towards model P450 IA system indu cers. These results suggest a possible pollutant-induced suppression o r inactivation of the P450 IA system in feral perch in Lake Jarnsjon.