Primers based on known multidrug resistance (MDR) protein sequences hy
bridized with Mytilus edulis cDNA and led to the amplification of two
major bands (approximatly 350 and 2500 bases long) corresponding to fr
agments of expected size as compared to human MDR genes. MDR protein l
evels in mussel tissues can be quantified with an ELISA test using the
monoclonal antibody C219.