Mh. Cui et al., HUMAN PAPILLOMAVIRUS IN CONDYLOMA ACCUMINATA AND OTHER BENIGN LESIONSOF THE FEMALE GENITAL-TRACT, Chinese medical journal, 107(9), 1994, pp. 703-708
PCR was used to detect (HPV) in condyloma accuminata (CA), pseudocondy
loma whose cause is unclear, and the other benign lesions in female ge
nital tract. The results showed that HPV prevalence rate in CA was 98.
2%, type 6 was in 11 was 85.7%, and that in pseudocondyloma, cervical
polyp, cervical erosion and chronic vaginitis was 40.4%, 76.2%, 77.3%
and 16.0%, respectively. Even in normal vaginal tissue, there existed
HPV subclinical infection. HPV prevalence rate in swabs from patient's
underwears and normal vaginal tissues was 73.6% and 54.0% respectivel
y. The investigation of estrogen receptor (ER) in CA tissue carried ou
t by immunohistochemical method found that positive ER was achieved in
most of CA, and few of normal vulvar tissues was found. This result i
ndicated that the occurrence of CA is probably related to estrogen.