The 75 year old patient suffered from perianal pruritus and weeping. H
e also had a temporary productive cough and a weight reduction of 9 kg
during the last six months. The diagnosis of an anorectal tuberculosi
s based on the histological proof of caseating granuloma with acid fas
t bacteriae from an anorectal fistula and on the cultural demonstratio
n of mycobacterium tuberculosis in the stool. The lung tuberculosis wa
s displayed by radiographic infiltrations in both upper lobes of the l
ung and by the radiometric and cultural positive proof of tuberculosis
bacteriae in sputum and gastric juice specimens. Both manifestations
of tuberculosis were regressive under a fourfold combination of tuberc
ulostatic therapy. Anorectal tuberculosis manifestations are extremely
rare and are predominately found in developing countries. However, du
e to the increasing number of immunocomprised patients such as HIV-pat
ients, an elevated incidence of tuberculosis has been observed. Theref
ore, a tuberculous origin should be considered for all chronic anorect
al lesions especially in immunocompromised patients.