The presence of O-antigen affects the adhesion of Serratia marcescens
cells to inert and biological surfaces. Mutants defective in the O-sid
e chain showed significant decreases in their ability to adhere to pla
stic and glass surfaces and to the surfaces of Foley urinary catheters
, compared with their respective parental strains. Similar results wer
e obtained when the ability to adhere human uroepithelial cells was te
sted.