BRONCHIECTASIS AND HOMOZYGOUS (P(1)ZZ) ALPHA(1)-ANTITRYPSIN DEFICIENCY IN A YOUNG MAN

Pulmonary complications of alpha(1)-antitrypsin deficiency are most co mmonly manifested by panlobular emphysema. This report describes histo logically proven bronchiectasis in a 21 year old man with massive haem optysis and homozygous deficiency of alpha(1)-antitrypsin. Neither pan lobular emphysema nor cirrhosis of the Liver were present. Bronchiecta sis must be considered part of the spectrum of the pulmonary pathology that may be encountered in individuals with and alpha(1)-antitrypsin deficiency.