A NOVEL SEQUENCE POLYMORPHISM IN EXON-8 OF THE HUMAN VITAMIN-D-BINDING PROTEIN (GC) GENE IN AN AFRICAN POPULATION

Authors
YUASA I KOFLER A BRAUN A BICHLMAIER R KAMMERER S CLEVE H
Citation
I. Yuasa et al., A NOVEL SEQUENCE POLYMORPHISM IN EXON-8 OF THE HUMAN VITAMIN-D-BINDING PROTEIN (GC) GENE IN AN AFRICAN POPULATION, JPN J HUM G, 40(1), 1995, pp. 149-151
Citations number
1
Categorie Soggetti
Genetics & Heredity
Journal title
Japanese journal of human genetics → ACNP
ISSN journal
09168478
Volume
40
Issue
1
Year of publication
1995
Pages
149 - 151
Database
ISI
SICI code
0916-8478(1995)40:1<149:ANSPIE>2.0.ZU;2-3
Abstract
A novel sequence polymorphism due to a T to C transition at the third nucleotide to the codon for Cys(283) of the vitamin D-binding protein (GC) gene assigned to chromosome 4q13-4q21.1 was revealed by sequence analysis. Population studies by single strand conformation polymorphis m (SSCP) analysis showed this GC-283.3 site was polymorphic in a black African population but monomorphic in a European population.