The ideal artificial heart valve still does not exist among the variou
s cardiac valves available to the clinician. Morbidity and mortality a
re directly related to the valve itself. Despite the promising hemodyn
amic results obtained in the 70s with pericardial prosthesis, these va
lves were progressively abandoned due to their poor long-term resistan
ce. Based on an analysis of the causes of failures, modifications were
made in the manufacturing method and current results with pericardial
valves has greatly improved, inciting new interest in their clinical
use. Today, the pericardium is recognized as a valid substitution mate
rial for bioprostheses. Results of long-term series should confirm cur
rent studies. Research is under way to determine how to improve perica
rdium longevity since tissue deterioration remains the limiting factor
.