We evaluated 44 patients with carpal tunnel syndrome and performed his
tological evaluations of tenosynovium taken at the time of carpal tunn
el release. Age, disease and work history, radiographs, and outcome we
re assessed. The clinical parameters were then compared with the histo
logic features to determine if the histology was predictive of the cli
nical course of carpal tunnel syndrome. We found no significance in th
e histologic changes in patients with carpal tunnel syndrome when age,
duration of symptoms, work history, radiographs, and outcome were eva
luated.