J. Friedrich et al., EFFECT OF DONOR AND RECIPIENT AGE ON THE RESULTS OF RENAL-TRANSPLANTATION, Deutsche Medizinische Wochenschrift, 120(14), 1995, pp. 467-471
In a retrospective study of 814 patients (349 women, 465 men) who had
received their first kidney transplant, early function rate as well as
transplant and patient survival rates were determined in relation to
age (up to 50 years: 530; 51-55 years: 140; 56-60 years: 83; over 60 y
ears: 61). The same rates were also grouped by donor age (> 16 years,
68 patients; 16-40 years, 387; 41-50 years, 165; 51-60 years, 144; ove
r 60 years, 50). The 5-year transplant function rate fell significantl
y with increasing donor age (P = 0.0001) from 78% (16-40 years) to 47%
over 60 years). For the same age groups the proportion of transplants
which never resumed their function rose from 8 to 28%. Age of recipie
nt had no influence on early function and 5-year transplant function r
ates. Thus, regardless of the recipient's age, higher donor age is an
independent risk factor for early and late results after transplantati
on.