A COMPARATIVE-STUDY OF THE USE OF ENSET AND POTATO STARCHES IN TABLETFORMULATIONS

Citation
T. Gebremariam et Na. Armstrong, A COMPARATIVE-STUDY OF THE USE OF ENSET AND POTATO STARCHES IN TABLETFORMULATIONS, Drug development and industrial pharmacy, 21(10), 1995, pp. 1211-1221
Citations number
9
Categorie Soggetti
Pharmacology & Pharmacy
ISSN journal
03639045
Volume
21
Issue
10
Year of publication
1995
Pages
1211 - 1221
Database
ISI
SICI code
0363-9045(1995)21:10<1211:ACOTUO>2.0.ZU;2-0
Abstract
Enset and potato starches have been compared as binding agents and dis integrants in tablets made with paracetamol and chloroquine phosphate. Tablet crushing strengths, friabilities and disintegration times have been measured. The results show that enset starch can be used both as a binding agent and disintegrant. It has a better binding ability tha n potato starch, giving tablets of lower porosity. However because of this, tablets containing enset starch disintegrate more slowly.